Oh N, Kim K, Kim SJ, Park I, Lee JE, Seo YS, An HJ, Kim HM*, Koh GY*. A Designed Angiopoietin-1 Variant, Dimeric CMP-Ang1 Activates Tie2 and Stimulates Angiogenesis and Vascular Stabilization in N-glycan Dependent Manner. Scientific Reports. 2015 Oct 19; 5:15291.
#Protein Science #Protein Engineering #Negative stain EM #Collaboration
Lee J, Chung J-H, Kim HM, Kim D-W, Kim H. Designed Nucleases for targeted genome editing. Plant Biotechnol J., 2015 Sep 15; DOI: 10.1111/pbi.12465.
#Protein Structure #Review #Collaboration
Yang KS, Sung BH, Park MK, Lee JH, Lim KJ, Park SC, Kim SJ, Kim HK, Sohn J-H, Kim HM*, Kim SC*. A recombinant lipase engineered with amphipathic and coiled-coil peptides. ACS Catal. 2015 July 17; DOI: 10.1021/cs502079g.
#Protein Science #Protein Engineering #Collaboration
Kim YN, Kim JA, Kim HM, Jung Y. Green fluorescent protein nanopolygons as monodisperse supramolecular assemblies of functional proteins with defined valency. Nature Communications. 2015 May 14; DOI: 10.1038/ncomms8134
#Protein Science #Protein Engineering #Negative stain EM #Collaboration
Kim YR, Kim S, Choi JW, Choi SY, Lee SH, Kim HM, Hahn SK, Koh GY, Yun SH. Bioluminescence-activated deep-tissue photodynamic therapy of cancer. Theranostics. 2015; 5(8):805-817.
#Negative stain EM #Drug Development #Cancer #Collaboration
SJ Park, J Oh, Y-K Kim, JH Park, JY Park, HK Hong, KH Park, J-E Lee, HM Kim, JY Chung, SJ Woo. Intraocular pharmacokinetics of intravitreal vascular endothelial growth factor-Trap in a rabbit model. Eye (Lond). 2015 Apr;29(4):561-8.
#Protein Science #Protein Engineering #Drug Development #Collaboration
Lim JS, Kim WI, Kang HC, Kim SH, Park AH, Park EK, Cho YW, Kim S, Kim HM, Kim JA, Kim J, Rhee H, Kang SG, Kim HD, Kim D, Kim DS, Lee JH. Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy. Nature Medicine. 2015 Apr; 21(4): 395-400
#Protein Structure #Human Disease #Collaboration
Ryu JK, Min D, Rah SH, Kim SJ, Park Y, KimH, Hyeon C, Kim HM, Jahn R, Yoon TY. Spring-Loaded Unraveling of a Single SNARE Complex by NSF in One Round of ATP Turnover. Science. 2015 Mar 27; 347(6229): 1485-1489.
#Protein Science #Protein Structure #Biophysics #Collaboration
Lee J, Kim C, Yang H, Park I, Oh N, Hua S, Jeong H, An H, Kim SC, Lee GM, Koh GY*, Kim HM*. Novel Glycosylated VEGF Decoy Receptor Fusion Protein, VEGF-Grab, Efficiently Suppresses Tumor Angiogenesis and Progression. Mol Cancer Ther. 2015 Feb;14(2):470-9. Selected as Issue Highlights.
#Protein Science #Protein Engineering #Drug Development #Collaboration
Ko JS, Pramanik G, Um JW, Shim JS, Lee D, Kim KH, Chung GY, Condomitti G, Kim HM, Kim H, de Wit J, Park KS, Tabuchi K, Ko J. PTPσ functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission. Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1874-9.
#Protein Science #Neuroscience #Collaboration
Do H, Kim SJ, Lee CW, Kim H, Park HH, Kim HM, Park H, Park H and Lee JH, Crystal structure of UbiX, an aromatic acid decarboxylase from the psychrophilic bacterium Colwellia psychrerythraea that undergoes FMN-induced conformational changes. Scientific Reports. 2015 Feb 03;5:8196.
#Protein Structure #Negative stain EM #Collaboration
Soh YM, Burmann F, Shin HC, Oda T, Jin KS, Toseland CP, Kim C, Lee H, Kim SJ, Kong MS, Durand-Diebold ML, Kim YG, Kim HM, Lee NK, Sato M, Oh BH, Gruber S. Molecular Basis for SMC Rod Formation and Its Dissolution upon DNA Binding. Mol Cell. 2015 Jan 22;57(2):290-303.
#Protein Structure #Negative stain EM #Collaboration
Lee H, Hong D, Choi JY, Kim JY, Lee SH, Kim HM, Yang SH, Choi IS. Layer-by-Layer-Based Silica Encapsulation of Individual Yeast with Thickness Control. Chem Asian J. 2015 Jan;10(1):129-32.
#EM #Collaboration
