Kwon MJ, Han MH, Bagley JA, Hyeon DY, Ko BS, Lee YM, Cha IJ, Kim SY, Kim DY, Kim HM, Hwang D, Lee SB, Jan YN. Coiled-coil structure-dependent interactions between polyQ proteins and Foxo lead to dendrite pathology and behavioral defects. Proc Natl Acad Sci U S A. 2018 Oct 22. pii: 201807206.
Kim HM*, Kim YM*. HMGB1: LPS Delivery Vehicle for Caspase-11-Mediated Pyroptosis (Preview). Immunity. 2018 Oct 16;49(4):582-584.
Yoon HR, Choi H, Choi YA, Kim JA, Jung J, Kim HM, Jung Y. Fabrication of Oligomeric Avidin Scaffolds for Valency-Controlled Surface Display of Functional Ligands. Angew Chem Int Ed Engl. 2018 Sep 17;57(38):12410-12414.
Yin GN, Jin H-R, Choi M-J, Limanjaya A, Ghatak K, Minh NN, Kwon M-H, Song K-M, Park HJ, Kim HM, Kwon Y-G, Ryu J-K and Suh J-K. Pericyte-Derived Dickkopf2 Regenerates Damaged Penile Neurovasculature Through an Angiopoietin-1-Tie2 Pathway. Diabetes. 2018 Jun;67(6):1149-1161.
Won SY, Kim HM*. Structural Basis for LAR-RPTP-Mediated Synaptogenesis. Mol Cells. 2018 Jul 31;41(7):622-630.
Lee JH, Park BS, Han KR, Biering SB, Kim SJ, Choi J, Seok JH, Alam I, Chung MS, Kim HM, Hwang S, Kim KH. Insight Into the Interaction Between RNA Polymerase and VPg for Murine Norovirus Replication. Front. Microbiol., 2018 Jul 03;9:1466.
Lee DH, Lee MY, Seo Y, Hong HJ, An HJ, Kang JS*, Kim HM*. Multi-paratopic VEGF decoy receptor have superior anti-tumor effects through anti-EGFRs and targeted anti-angiogenic activities. Biomaterials. 2018 Apr 16;171:34-45.
Seo BA, Lee JH, Kim HM*, Kang MG*. Neuronal calcium channel α1 subunit interacts with AMPA receptor, increasing its cell surface localization. Biochem Biophys Res Commun. 2018 Apr 6;498 (3):402-408.
Ahn B, Lee S-G, Yoon HR, Lee JM, Oh HJ, Kim HM*, Jung Y*. Four-fold Channel-Nicked Human Ferritin Nanocages for Active Drug Loading and pH-Responsive Drug Release. Angew Chem Int Ed Engl. 2018 Mar 5;57(11):2909-2913.
Kim SY, Jeong JM, Kim SJ, Seo W, Kim MH, Choi WM, Yoo W, Lee JH, Shim YR, Yi HS, Lee YS, Eun HS, Lee BS, Chun K, Kang SJ, Kim SC,7, Gao B, Kunos G, Kim HM, Jeong WI. Pro-inflammatory hepatic macrophages generate ROS through NADPH oxidase 2 via endocytosis of monomeric TLR4-MD2 complex. Nat Communications. 2017 Dec 21;8(1):2247.
Ghatak K, Yin GN, Choi MJ, Limanjaya A, Minh NN, Ock J, Song KM, Kang DH, Kwon YG, Kim HM, Ryu JK, Suh JK. Dickkopf2 rescues erectile function by enhancing penile neurovascular regeneration in a mouse model of cavernous nerve injury. Sci Rep. 2017 Dec 19;7(1):17819.
Won SY, Kim CY, Kim D, Ko J, Um JW, Lee SB, Buck M, Kim E, Heo WD*, Lee JO*, Kim HM*. LAR-RPTP Clustering Is Modulated by Competitive Binding between Synaptic Adhesion Partners and Heparan Sulfate. Frontiers in Molecular Neuroscience. 2017 Oct 13;10:327.
Joo K, Park SJ, Choi Y, Lee JE, Na YM, Hong HK, Park KH, Kim HM*, Chung JY*, and Woo SJ*. Role of the Fc Region in the Vitreous Half-life of Anti-VEGF Drugs. Investigative Ophthalmology & Visual Science. 2017 Aug 1;58(10):4261-4267.
Kim JA, Kim D, Won SY, Han KA, Park D, Cho E, Yun N, An HJ, Um JW, Kim E, Lee JO, Ko J*, Kim HM*. Structural Insights into Modulation of Neurexin-Neuroligin Trans-synaptic Adhesion by MDGA1/Neuroligin-2 Complex. Neuron. 2017 Jun 21;94(6):1121-1131.e6. doi: 10.1016/j.neuron.2017.05.034. Selected as Issue Highlights.
Sung PS, Hong SH, Chung JH, Kim S, Park SH, Kim HM, Yoon SK, Shin EC. IFN-λ4 potently blocks IFN-α signalling by ISG15 and USP18 in hepatitis C virus infection. Sci Rep. 2017 Jun 19;7(1):3821.
Kim SJ, Kim HM*. Dynamic lipopolysaccharide transfer cascade to TLR4/MD2 complex via LBP and CD14. BMB Rep. 2017 Feb;50(2):55-57.
Ryu J-K, Kim SJ, Rah S-H, Kang JI, Jung HE, Lee D, Lee HK, Lee J-O, Park BS, Yoon T-Y*, Kim HM*. Reconstruction of LPS transfer cascade reveals structural determinants within LBP, CD14 and TLR4-MD2 for efficient LPS recognition and transfer. Immunity. 2017 Jan 17;46(1):38-50. doi: 10.1016/j.immuni.2016.11.007. *recommended by Faculty of 1000 Biology
Lee H, Hong D, Cho H, Kim JY, Park JH, Lee SH, Kim HM, Fakhrullin RF, Choi IS. Turning Diamagnetic Microbes into Multinary Micro-Magnets: Magnetophoresis and Spatio-Temporal Manipulation of Individual Living Cells. Sci. Rep. 2016 Dec 5;6:38517. doi: 10.1038/srep38517.
Das ND, Yin GN, Choi MJ, Song KM, Park JM, Limanjaya A, Ghatak K, Minh NN, Ock J, Park SH, Kim HM, Ryu JK, Suh JK. Effectiveness of Intracavernous Delivery of Recombinant Human Hepatocyte Growth Factor on ErectileFunction in the Streptozotocin-Induced Diabetic Mouse. J Sex Med. 2016 Nov;13(11):1618-1628. doi: 10.1016/j.jsxm.2016.09.017.
Kang H, Han KA, Won SY, Kim HM, Lee Y-H, Ko J, Um JW. Slitrk Missense Mutations Associated with Neuropsychiatric Disorders Distinctively Impair Slitrk Trafficking and Synapse Formation. Front. Mol. Neurosci. 2016 Oct 20;9:104.
Lie E, Ko JS, Choi SY, Roh J, Cho YS, Noh R, Kim D, Li Y, Kang H, Choi TY, Nam J, Mah W, Lee D, Lee SG, Kim HM, Kim H, Choi SY, Um JW, Kang MG, Bae YC, Ko J and Kim E. SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion. Nature Communications. 2016 Aug 2;7:12328.
Choi Y, Nam J, Whitcomb DJ, Song YS, Kim D, Jeon S, Um JW, Lee SG, Woo J, Kwon SK, Li Y, Mah W, Kim HM, Ko J, Cho K, Kim E. SALM5 trans-synaptically interacts with LAR-RPTPs in a splicing-dependent manner to regulate synapse development. Sci Rep. 2016 May 26;6:26676.
Han KA, Woo D, Kim S, Choii G, Jeon S, Won SY, Kim HM, Heo WD, Um JW, Ko J. Neurotrophin-3 regulates synapse development by modulating TrkC-PTPσ synaptic adhesion and intracellular signaling pathways. J. Neurosci. 2016 Apr 27;36(17):4816-31.
Lee JM, Kim JA, Yen TC, Lee IH, Ahn B, Lee Y, Hsieh CL, Kim HM, Jung Y. A Rhizavidin Monomer with Nearly Multimeric Avidin-Like Binding Stability Against Biotin Conjugates. Angew Chem Int Ed Engl. 2016 Mar 1;55(10):3393-7.
Oh N, Kim K, Kim SJ, Park I, Lee JE, Seo YS, An HJ, Kim HM*, Koh GY*. A Designed Angiopoietin-1 Variant, Dimeric CMP-Ang1 Activates Tie2 and Stimulates Angiogenesis and Vascular Stabilization in N-glycan Dependent Manner. Scientific Reports. 2015 Oct 19; 5:15291.
Lee J, Chung J-H, Kim HM, Kim D-W, Kim H. Designed Nucleases for targeted genome editing. Plant Biotechnol J., 2015 Sep 15; DOI: 10.1111/pbi.12465.
Yang KS, Sung BH, Park MK, Lee JH, Lim KJ, Park SC, Kim SJ, Kim HK, Sohn J-H, Kim HM*, Kim SC*. A recombinant lipase engineered with amphipathic and coiled-coil peptides. ACS Catal. 2015 July 17; DOI: 10.1021/cs502079g.
Kim YN, Kim JA, Kim HM, Jung Y. Green fluorescent protein nanopolygons as monodisperse supramolecular assemblies of functional proteins with defined valency. Nat Commun. 2015 May 14; DOI: 10.1038/ncomms8134
Kim YR, Kim S, Choi JW, Choi SY, Lee SH, Kim HM, Hahn SK, Koh GY, Yun SH. Bioluminescence-activated deep-tissue photodynamic therapy of cancer. Theranostics. 2015; 5(8):805-817.
SJ Park, J Oh, Y-K Kim, JH Park, JY Park, HK Hong, KH Park, J-E Lee, HM Kim, JY Chung, SJ Woo. Intraocular pharmacokinetics of intravitreal vascular endothelial growth factor-Trap in a rabbit model. Eye (Lond). 2015 Apr;29(4):561-8.
Lim JS, Kim WI, Kang HC, Kim SH, Park AH, Park EK, Cho YW, Kim S, Kim HM, Kim JA, Kim J, Rhee H, Kang SG, Kim HD, Kim D, Kim DS, Lee JH. Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy. Nat Med. 2015 Apr; 21(4): 395-400
Ryu JK, Min D, Rah SH, Kim SJ, Park Y, KimH, Hyeon C, Kim HM, Jahn R, Yoon TY. Spring-Loaded Unraveling of a Single SNARE Complex by NSF in One Round of ATP Turnover. Science. 2015 Mar 27; 347(6229): 1485-1489.
Lee J, Kim C, Yang H, Park I, Oh N, Hua S, Jeong H, An H, Kim SC, Lee GM, Koh GY*, Kim HM*. Novel Glycosylated VEGF Decoy Receptor Fusion Protein, VEGF-Grab, Efficiently Suppresses Tumor Angiogenesis and Progression. Mol Cancer Ther. 2015 Feb;14(2):470-9. Selected as Issue Highlights.
Ko JS, Pramanik G, Um JW, Shim JS, Lee D, Kim KH, Chung GY, Condomitti G, Kim HM, Kim H, de Wit J, Park KS, Tabuchi K, Ko J. PTPσ functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission. Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1874-9.
Do H, Kim SJ, Lee CW, Kim H, Park HH, Kim HM, Park H, Park H and Lee JH, Crystal structure of UbiX, an aromatic acid decarboxylase from the psychrophilic bacterium Colwellia psychrerythraea that undergoes FMN-induced conformational changes. Scientific Reports. 2015 Feb 03;5:8196.
Soh YM, Burmann F, Shin HC, Oda T, Jin KS, Toseland CP, Kim C, Lee H, Kim SJ, Kong MS, Durand-Diebold ML, Kim YG, Kim HM, Lee NK, Sato M, Oh BH, Gruber S. Molecular Basis for SMC Rod Formation and Its Dissolution upon DNA Binding. Mol Cell. 2015 Jan 22;57(2):290-303.
Lee H, Hong D, Choi JY, Kim JY, Lee SH, Kim HM, Yang SH, Choi IS. Layer-by-Layer-Based Silica Encapsulation of Individual Yeast with Thickness Control. Chem Asian J. 2015 Jan;10(1):129-32.
Um JW, Kim KH, Park BS, Choi Y, Kim D, Kim CY, Kim SJ, Kim MH, Ko JS, Lee S-G, Choii G, Nam J, Heo WD, Kim E, Lee J-O, Ko J*, Kim HM*. Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion. Nat Commun. 2014 Nov 14;5:5423. doi: 10.1038/ncomms6423.
Kim SJ, Cho JH, Son EJ, Kim SJ, Kim HM, Lee KE, Suh SW, Kim EK. Structural basis for OTU1 binding to p97/VCP. J. Bio. Chem. 2014 May 2;289(18):12264-74.
Lee MK, Kim SW, Lee JH, Cho YJ, Kim DE, Lee BI, Kim HM, Lee MG, Heo K. A newly discovered LGI1 mutation in Korean family with autosomal dominant lateral temporal lobe epilepsy. Seizure. 2014 Jan;23(1):69-73.
Park S*, Li X*, Kim HM*, Singh CR, Tian G, Hoyt MA, Lovell S, Battaile KP, Zolkiewski M, Coffino P, Roelofs J, Cheng Y, Finley D. Reconfiguration of the proteasome during chaperone-mediated assembly. Nature, 2013 May 23; 497(7450):512-6. * Equally contributed to this work.
Kwon MS, Park BO, Kim HM, Kim SH, Leucine-rich repeat-containing G-protein coupled receptor 5/GPR49 activates G12/13-Rho GTPase pathway, Mol Cells. 2013 Sep;36(3):267-72.
Kim D, Park J, Kim SJ, Soh YM, Kim HM, Oh BH, Song JJ. Brucella immunogenic BP26 forms a channel-like structure, J Mol Biol. 2013 Apr 12;425(7):1119-26.
Schneidman-Duhovny D, Rossi A, Avila-Sakar A, Kim SJ, Velázquez-Muriel J, Strop P, Liang H, Krukenberg KA, Liao M, Kim HM, Sobhanifar S, Dötsch V, Rajpal A, Pons J, Agard DA, Cheng Y, Sali A A Method for Integrative Structure Determination of Protein-Protein Complexes. Bioinformatics. 2012 Oct 23.
An HJ, Kim YJ, Song DH, Park BS, Kim HM, Lee JD, Paik SG, Lee JO, Lee H. Crystallographic and mutational analysis of the CD40-CD154 complex and its implications for receptor activation. J Biol Chem. 2011 Apr 1;286(13):11226-35.
Kim HM, Yu Y, Cheng Y. Structure characterization of the 26S proteasome. Biochim Biophys Acta. - Gene Regulatory Mechanisms, 2011 Feb;1809(2):67-79.
Koh YJ, Kim HZ, Hwang SI, Lee JE, Oh N, Jung K, Kim M, Kim KE, Kim H, Lim NK, Jeon CJ, Lee GM, Jeon BH, Nam DH, Sung HK, Nagy A, Yoo OJ, Koh GY. Double Antiangiogenic Protein, DAAP, Targeting VEGF-A and Angiopoietins in Tumor Angiogenesis, Metastasis, and Vascular Leakage. Cancer cell, 2010 Aug 17 ;18(2): 171–184.
Yu Y, Smith DM, Kim HM, Rodriguez V, Goldberg AL, Cheng Y. Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions. EMBO J. 2010 Feb 3;29(3):692-702.
Min SH, Kim DM, Heo YS, Kim HM, Kim IC, Yoo OJ. Downregulation of p53 by phosphatase of regenerating liver 3 is mediated by MDM2 and PIRH2. Life Sci. 2010 Jan 2;86(1-2):66-72.
Jung K, Lee JE, Kim HZ, Kim HM, Park BS, Hwang SI, Lee JO, Kim SC, Koh GY. Toll-like receptor 4 decoy, TOY, attenuates gram-negative bacterial sepsis. PLoS One. 2009 Oct 9;4(10).
Kim HZ, Jung K, Kim HM, Cheng Y, Koh GY. A Designed Angiopoietin-2 Variant, Pentameric COMP-Ang2, Strongly Activates Tie2 Receptor and Stimulates Angiogenesis. Biochim Biophys Acta. 2009 May; 1793(5):772-80.
Park BS, Song DH, Kim HM, Choi BS, Lee H, Lee JO. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature. 2009 Apr 30; 458(7242):1191-5 *Spotlight ACS Chem. Biol., 2009, 4 (4), pp 238–240, *recommended by Faculty of 1000 Biology.
Min SH, Kim DM, Heo YS, Kim YI, Kim HM, Kim J, Han YM, Kim IC, Yoo OJ. New p53 target, phosphatase of regenerating liver 1 (PRL-1) downregulates p53. Oncogene. 2009 Jan 29;28(4):545-54.
Lee KE, Kim HM, Lee JO, Jeon H, Han SS. Regulation of CD40 reconstitution into a liposome using different ratios of solubilized LDAO to lipids. Colloids Surf B Biointerfaces. 2008 Mar 15;62(1):51-7.
Kim HM, Park BS, Kim JI, Kim SE, Lee J, Oh SC, Enkhbayar P, Matsushima N, Lee H, Yoo OK, Lee JO. Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran. Cell, 2007 Sep 7; 130(5):906-17 *Spotlight ACS Chem. Biol., 2007, 2 (10), pp 642–645, *recommended by Faculty of 1000 Biology.
Jin MS, Kim SE, Heo JY, Lee ME, Kim HM, Paik SG, Lee H, Lee JO. Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide. Cell. 2007 Sep 21; 130(6):1071-82 *recommended by Faculty of 1000 Biology.
Kim HM, Oh SC, Lim KJ, Kasamatsu J, Heo JY, Park BS, Lee H, Yoo OJ, Kasahara M, Lee JO. Structural diversity of the hagfish variable lymphocyte receptors. J. Biol. Chem. 282(9): 6726-32 (2007).
Yoon MK, Kim HM, Choi G, Lee JO, Choi BS. Structural basis for the conformational integrity of the Arabidopsis thaliana HY5 leucine zipper homodimer. J. Biol. Chem. 282(17): 12989-3002 (2007).
Kim HM, Yu KS, Lee ME, Shin DR, Kim YS, Paik SG, Yoo OJ, Lee H, Lee JO. Crystal structure of the BAFF-BAFF-R complex and its implications for receptor activation. Nat. Struct. Biol. 10(5): 342-8 (2003) * recommended by Faculty of 1000 Biology.
Kim HM, Shin DR, Yoo OJ, Lee H, Lee JO. Crystal structure of Drosophila angiotensin I-converting enzyme bound to captopril and lisinopril. FEBS Lett. 538(1-3): 65-70 (2003).
